Drug Standards
AdipoGen Ketoconazole
Chemical. CAS 65277-42-1. Formula C26H28Cl2N4O4. MW 531.43. Ketoconazole is a broad-spectrum triazole antifungal agent that has activity against C. albicans, C. krusei, C. tropicalis, C. glabrata, C. parapsilosis, C. neoformans and A. fumigatus strains IC50s = 0.031-8 µg/ml. It inhibits the fungal cytochrome P450 CYP isoform CYP51, also known as lanosterol 14alpha-demethylase, which arrests ergosterol biosynthesis at the fungal membrane. This interaction inhibits ergosterol synthesis and results in increased fungal cellular permeability. Ketoconazole also inhibits human CYP3A4 IC50 = 0.54 µM. Formulations containing ketoconazole have been used in the treatment of fungal infections. Ketoconazole blocks in humans activity of several enzymes necessary for the conversion of cholesterol to steroid hormones such as testosterone and cortisol.
Medchemexpress LLC Larotrectinib | 1223403-58-4 | 99.9% | 10 MG
Larotrectinib is an ATP-competitive oral, selective inhibitor of the tropomyosin-related kinase (TRK) family receptors. It demonstrates low nanomolar 50% inhibitory concentrations against all three isoforms (TRKA, B, and C) and exhibits 1,000-fold or greater selectivity relative to other kinases. This product is for research use only.
- Targets TrkA, TrkB, and TrkC
- Exhibits antiproliferative activity against various cell lines
- Demonstrates dose-dependent inhibition of cell proliferation
- Has low brain penetration in animal studies
- Well tolerated in GLP toxicology studies
- Reduces tyrosine phosphorylation of TRKA and downstream signal transduction in tumors
- Shows dose-dependent tumor inhibition in athymic nude mice
- Reduces leukemic infiltration in bone marrow and spleen in mice
Medchemexpress LLC Bromfenac sodium hydrate | 120638-55-3 | 99.9% | 200 MG
Bromfenac sodium hydrate is a potent and orally active inhibitor of COX, with IC50s of 5.56 and 7.45 nM for COX-1 and COX-2, respectively. It can be used in ocular inflammation research.
- Potent and orally active inhibitor of COX.
- Can be used in ocular inflammation research.
- Available in solid and solution forms.
Medchemexpress LLC Voriconazole | 137234-62-9 | MFCD00905717 | 99.9% | 349.31 g/mol | C16H14F3N5O | 10 MG
Voriconazole analytical standard is a second-generation, broad-spectrum triazole antifungal provided as a high-purity reference material for research and analytical testing. It is intended for use in HPLC and other analytical assays to support quantitation and method validation.
- Analytical standard for research and analytical applications.
- High purity (99.9%).
- Molecular formula C16H14F3N5O.
- Molecular weight 349.31 g/mol.
- CAS number 137234-62-9.
- Supplied in small pack sizes suitable for analytical use, e.g., 10 mg.
- Antifungal mechanism: inhibits 14-α-lanosterol demethylation.
Medchemexpress LLC Ethyl linolenate | 1191-41-9 | 306.48 | 500 MG
Ethyl linolenate is a fatty acid ethyl ester (FAEE) that inhibits the cellular production of melanin with an IC50 of 70 μM, demonstrating anti-melanogenesis effects. It significantly blocks Forskolin-induced melanogenesis and inhibits tyrosinase activity. This product is for research use only.
- Fatty acid ethyl ester (FAEE)
- Inhibits cellular production of melanin with an IC50 of 70 μM
- Anti-melanogenesis effects
- Significantly blocks Forskolin-induced melanogenesis
- Inhibits tyrosinase activity
- Purity: 98.0%
Sigma Aldrich Fine Chemicals Biosciences Rivaroxaban United States200mg
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
Sigma Aldrich Fine Chemicals Biosciences Dihydrocapsaicin United St25MG
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Ph
Sigma Aldrich Fine Chemicals Biosciences Carmustine United States P5MG
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.for further information and support please go to the website of the issuing Pharmacopoeia.
![eMolecules 496775-62-3 | Eltrombopag Olamine | AA Blocks LLC564.643 | C29H36N6O6 | 0.000 | NCCO.NCCO.Cc1[nH]n(-c2ccc(C)c(C)c2)c(=O)c1NN=C1C=CC=C(C1=O)c1cccc(c1)C(O)=O | 250mg | 795057738](https://assets.fishersci.com/TFS-Assets/CCG/product-images/NC3966655.jpg-250.jpg)
eMolecules 496775-62-3 | Eltrombopag Olamine | AA Blocks LLC564.643 | C29H36N6O6 | 0.000 | NCCO.NCCO.Cc1[nH]n(-c2ccc(C)c(C)c2)c(=O)c1NN=C1C=CC=C(C1=O)c1cccc(c1)C(O)=O | 250mg | 795057738
Eltrombopag Olamine | AA Blocks LLC | 496775-62-3564.643 | C29H36N6O6 | 0.000 | NCCO.NCCO.Cc1[nH]n(-c2ccc(C)c(C)c2)c(=O)c1NN=C1C=CC=C(C1=O)c1cccc(c1)C(O)=O | 250mg | 795057738
Cayman Chemical FamcIclovIr 50mg
An orally bioavailable prodrug form of penciclovir; oxidized in vitro by human, guinea pig, and rat liver aldehyde oxidase; in rats the peak concentrations of penciclovir in plasma (mean 3.5 μg/ml) occur in 0.5 hours (40 mg/kg); in dogs the peak concentrations of penciclovir in plasma (mean 4.4 μg/ml) occur in 3 hours (25 mg/kg)
Medchemexpress LLC (3S,4S)-Tofacitinib | 1092578-47-6 | MFCD11035920 | 99.8% | 312.37 g/mol | C16H20N6O | 10 MG
(3S,4S)-Tofacitinib is the S-enantiomer of the JAK inhibitor tofacitinib and is provided as a research reference compound for biochemical and cellular studies. It is reported to be less active than the clinical racemate and is characterized by CAS 1092578-47-6, formula C16H20N6O, and molecular weight 312.37 g/mol.
- Enantiomeric reference for JAK signaling studies.
- High purity (99.75%) suitable for analytical and biochemical assays.
- Molecular formula C16H20N6O and molecular weight 312.37 g/mol.
- Supplied as a 10 mg research quantity.
- Useful as a reference standard for selectivity and potency comparisons.
Sigma Aldrich Fine Chemicals Biosciences Naproxen US Pha200mg
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.for further information and support please go to the website of the issuing Pharmacopoeia.
Medchemexpress LLC Tosylate-DPA-714 | 958233-17-5 | 97.0% | 10 MG
Tosylate-DPA-714 is the tosylate analog of DPA-714 used as a precursor for synthesizing 18F-labeled DPA-714, a translocator protein (TSPO)-selective ligand for neuroinflammation imaging research. Supplied for research use only in small laboratory quantities.
- Precursor for 18F radiolabeling of DPA-714.
- High purity (HPLC), approximately 97.0%.
- Molecular formula C29H34N4O5S; molecular weight 550.67 g·mol⁻¹.
- Supplied in small quantities suitable for synthesis (e.g., 10 MG).
- Intended for research use only; not for human or clinical use.
Medchemexpress LLC Larotrectinib | 1223403-58-4 | 99.9% | 10 UMOL
Larotrectinib (LOXO-101) is an ATP-competitive, oral, and selective inhibitor of the tropomyosin-related kinase (TRK) family receptors. It demonstrates low nanomolar 50% inhibitory concentrations against all three isoforms (TRKA, B, and C) and is intended for research use only.
- Inhibitor of TRK family receptors (TRKA, B, and C)
- Exhibits low nanomolar IC50 against TRK isoforms
- For research use only
- Target: Trk Receptor, Apoptosis, Reference Standards
- Pathway: Neuronal Signaling, Protein Tyrosine Kinase/RTK, Apoptosis
- Molecular formula: C21H22F2N6O2
- Molecular weight: 428.44
AdipoGen Moxifloxacin hydrochloride
Chemical. CAS 186826-86-8. Formula C21H24FN3O4 . HCl. MW 401.43 . 36.46. Moxifloxacin is a fourth-generation synthetic broad-spectrum fluoroquinolone antibiotic. It is used against both Gram-positive and Gram-negative bacteria and to treat bacterial infections associated with bronchitis, sinusitis, and other conditions. Fluoroquinolones stabilize DNA strand breaks created by DNA gyrase Topo II and topoisomerase IV by binding to the enzyme-DNA complex. Compared to mammalian DNA gyrase, moxifloxacin has 100 times higher affinity for bacterial DNA gyrase. Can also be used as reference compound.